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New Meta Study Confirms Red Wine Health Benefits

Two new studies published in the journal Nature this week confirm that resveratrol can prevent the diseases of aging and increase Healthspan.
Detroit, MI, United States of America (prbd.net) 29/09/2011
Two new meta studies published in the Journal Nature, one authored by Dr, David Gems, and the second one by Drs. Auwerx and Canto, examine previous studies of red wine's ability to promote human health and longevity. The compound which is contained in red wine which was the subject of the study is called resveratrol. Resveratrol was first identified as an activator of enzymes known as sitruins by Dr David Sinclair of Harvard and his work was also publiched in the prestigious journal Nature in 2006. Since that time over 5,000 additional studies of resveratrol have been undertaken. The vast majority of these studies elucidate impressive potential health benefits of the red wine molecule. Although most of these studies were done on animals or in the lab, however since 2009 a significant number of human clinical trials, using a purified form of resveratrol called transmax resveratrol, have been undertaken by institutions such as Albert Einstein Medical College, the University of Ottawa, and Northumbria Universit . In these clinical trials resveratrol was shown to improve blood glucose tolerance in pre diabetic subjects, increase brain blood flow in university students, increase fitness in both training and sedentary subjects and to have a wide range of other beneficial health effects.

In the two new Nature studies it was confirmed that resveratrol does activate the so-called anti-aging genes Sirt 1 and 2, but that the primary benefits of this effect is to promote resistance to the diseases of aging such as diabetes and other chronic conditions, not necessarily to directly increase lifespan. Studies on human longevity are extremely difficult to conduct due to the inability of the researchers to control for the thousands of factors which influence lifespan. The medical community prefers to focus on Healthspan, which is the number of years a person lives free of the debilitating diseases which often accompany the later years of a person's life. The idea is that if diseases including cancer, diabetes, heart disease and Alzheimer's disease can be prevented one's quality of life is dramatically improved and the cost of health care to the nation is greatly reduced. Dr. Auwerx stated “Similarly, indirect activation of SIRT1 by the compound resveratrol protects against metabolic and age-related diseases.” He goes on to state “SIRT1 activation remains a promising approach to delaying general age-related physiological decline and to treating numerous inherited and acquired diseases...

At this point the jury may still be out on whether resveratrol will make humans live longer, however if it prevents an individual from contracting cancer or diabetes or one of the other diseases of aging, for that person it will certainly increase improve both health span and quality of life, if not his life span.

One thing is clear. As the new study points out, The astonishing ability of SIRT1 to enhance 'healthspan' by promoting metabolic fitness will also guarantee it a long life as a subject for further exciting research.
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